Effectiveness of corifollitropin alfa used for ovarian stimulation of poor responder patients
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چکیده
منابع مشابه
Effectiveness of corifollitropin alfa used for ovarian stimulation of poor responder patients
PURPOSE To evaluate the efficiency and efficacy of corifollitropin alfa (follicle-stimulating hormone-carboxy terminal peptide) in the treatment of poor responder patients. METHODS A total of 85 poor responder patients with a mean age 40.2±3.9 years entered our assisted fertilization program. The patients were prospectively randomized into two groups based on the ovarian stimulation regimen u...
متن کاملCorifollitropin alfa followed by rFSH in a GnRH antagonist protocol for poor ovarian responder patients: an observational pilot study.
OBJECTIVE To identify whether women with poor ovarian response may benefit from treatment with corifollitropin alfa in a GnRH antagonist protocol. DESIGN Retrospective pilot study. SETTING University-based tertiary care center. PATIENT(S) Poor ovarian responders fulfilling the Bologna criteria developed by European Society for Human Reproduction and Embryology Consensus Group. INTERVENT...
متن کاملComparison of corifollitropin alfa and daily recombinant follicle-stimulating hormone in poor responder patients undergoing in vitro fertilization cycles
Objective The aim of this study was to compare the effect of corifollitropin alfa (CFA) and recombinant follicle-stimulating hormone (rFSH) in poor-responder patients undergoing antagonist cycles. Materials and Methods The study was a retrospective analysis of the treatment results of 214 poor responder patients who had been admitted to the In Vitro Fertilization Unit of İzmir Medical Park Ho...
متن کاملThe role of corifollitropin alfa in controlled ovarian stimulation for IVF in combination with GnRH antagonist
Corifollitropin alfa is a synthetic recombinant follicle-stimulating hormone (rFSH) molecule containing a hybrid beta subunit, which provides a plasma half-life of ∼65 hours while maintaining its pharmocodynamic activity. A single injection of corifollitropin alfa can replace daily FSH injections for the first week of ovarian stimulation for in vitro fertilization. Stimulation can be continued ...
متن کاملCorifollitropin alfa: a novel long-acting recombinant follicle-stimulating hormone agonist for controlled ovarian stimulation.
The advent of recombinant technology has made the production of modified proteins with desired properties possible. Corifollitropin alfa is a successful example of the first available long-acting, follicle stimulating hormone. Corifollitropin alfa has prolonged half-life and a slower absorption rate, but has the same receptor-binding and biological activity as recombinant FSH (rFSH). Its applic...
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ژورنال
عنوان ژورنال: International Journal of Women's Health
سال: 2016
ISSN: 1179-1411
DOI: 10.2147/ijwh.s117577